THJ-018 Chemical Powder


THJ-018 Chemical Powder

THJ-018 Chemical Powder

A synthetic cannabinoid that is the indazole analogue of JWH-018 and sold online as a designer drug. THJ-018 is high quality Research Chemicals.

THJ-018, or 1-naphthalenyl(1-pentyl-1H-indazol-3-yl)-methanone, is a synthetic cannabinoid containing a substituted indazole structure. Also substituted at R1 with a pentyl chain. Additionally, the indazole core is substituted at R3 with a carbonyl group which is also bonded to a napthalene moeity. Napthalene is a bicyclic structure of two fused benzene rings. This carbonyl bridge of THJ-018 classifies it as a ketone. THJ-018 is an analog of JWH-018 in which the core indole structure is substituted with an indazole base.

Like other cannabinoids, it is insoluble in water but dissolves in ethanol and liquid.

Although this substance has not been formally studied, from analysis of the structure, it is presumed that THJ-018 has a similar binding profile to that of JWH-018 and matches many of the in vivo properties of Δ9-THC. As with JWH-018, THJ-018 exhibits its range of effects via full agonism of both the CB1 and CB2 cannabinoid receptors, with some selectivity for CB2. THJ-018 is around 5x the potency of Δ9-THC. However, the role of these interactions and how they result in the cannabinoid high experience continues to remain elusive.


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