JWH-250 Research Chemical


JWH-250 Research Chemical

JWH-250 Research Chemical or (1-pentyl-3-(2-methoxyphenylacetyl)indole) is an analgesic chemical from the phenylacetylindole family. Thus acts as a cannabinoid agonist at both the CB1 and CB2 receptors. Also with a Ki of 11 nM at CB1 and 33 nM at CB2. Unlike many of the older JWH series compounds, this compound does not have a naphthalene ring, instead occupying this position with a 2′-methoxy-phenylacetyl group, making JWH-250 a representative member of a new class of cannabinoid ligands. Other 2′-substituted analogues such as the methyl, chloro and bromo compounds are also active and somewhat more potent.

We also have JWH 307 is a (1-naphthoyl) pyrrole cannabimimetic that potently activates both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors (Kivalues of 7.7 and 3.3 nM, respectively). Its physiological, neurological, and toxicological properties have not been evaluated. Intended for forensic and research applications. Kindly contact us via the contact form for more information.

JWH-250 – also considered a Schedule 9 prohibited substance in Australia under the Poisons Standard (October 2015). A Schedule 9 substance is a substance which may be abused or misused, the manufacture, possession, sale or use of which should be prohibited by law except when required for medical or scientific research, or for analytical, teaching or training purposes with approval of Commonwealth and/or State or Territory Health Authorities.


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