Hydroxilimine Research Chemical



Hydroxilimine Research Chemical

Hydroxilimine Research Chemical

A reactive chemical with formula NH2OH. It can be considered a hybrid of ammonia and water due to parallels it shares with each. At room temperature pure NH2OH is ordinarily a white, unstable crystalline, hygroscopic compound; however it is almost always encountered as an aqueous solution.

Hydroxylamine tends to be explosive, and the nature of the hazard is not entirely understood. At least two factories dealing in hydroxylamine have been destroyed since 1999 with loss of life. It is known, however, that ferrous and ferric iron accelerate the decomposition of 50% NH2OH solutions. Hydroxylamine and its derivatives are more safely handled in the form of salts.

NH2OH is an intermediate in biological nitrification. The oxidation of NH3 is mediated by HAO (hydroxylamine oxidoreductase).

Hydroxylamine and its salts are commonly used as reducing agents in a myriad of organic and inorganic reactions. They can also act as antioxidants for fatty acids. Some non-chemical uses include removal of hair from animal hides and photography developing solutions.

The nitrate salt, hydroxylammonium nitrate, is being researched as a rocket propellant, both in water solution as a monopropellant and in its solid form as a solid propellant.This is to probe functional areas of genes to elucidate what happens if their functions are broken. Nowadays other mutagens are used. Hydroxylamine can also be used to highly selectively cleave asparaginyl-glycine peptide bonds in peptides and proteins. It also bonds to and permanently disables (poisons) heme-containing enzymes. It is used as an irreversible inhibitor of the oxygen-evolving complex of photosynthesis on account of its similar structure to water.

In the semiconductor industry, hydroxylamine is often a component in the “resist stripper” which removes photoresist after lithography.


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