Ethylphenidate Powder (also known as EPH) – a novel stimulant substance of the piperidine class that produces traditional stimulant effects when administered.
Also a central nervous system stimulant and an analog of methylphenidate. It acts as a dopamine reuptake inhibitor and norepinephrine reuptake inhibitor. It is also produced in the body when methylphenidate is taken with ethanol.
Best known a closely related analog of methylphenidate (brand names Ritalin, Concerta). The two substances have very similar pharmacological mechanisms. But discernible differences in their subjective effects with ethylphenidate often considered as recreational.
Ethylphenidate – most commonly distributed as a research chemical by online vendors, due to its grey-area legal status in certain countries.
Used as a psychostimulant for the treatment of attention-
Ethylphenidate acts as both a dopamine reuptake inhibitor and norepinephrine reuptake inhibitor. This means it effectively boosts the levels of the norepinephrine and dopamine neurotransmitters in the brain by binding to and partially blocking the transporter proteins that normally remove those monoamines from the synaptic cleft. This allows dopamine and norepinephrine to accumulate within the brain, resulting in stimulating and euphoric effects.
It has been found that ethylphenidate is more selective to the dopamine transporter (DAT) than methylphenidate, having approximately the same efficacy as the parent compound, but with significantly less activity on the norepinephrine transporter (NET). Its dopaminergic pharmacodynamic profile is nearly identical to methylphenidate and is primarily responsible for its euphoric and reinforcing effects.