4-CEC Research Chemical



4-CEC Research Chemical

4-CEC Research Chemical

Also known as 4′-Chloroethcathinone. A chemical entity belonging to the substituted cathinone family of stimulants. Unlike many of its contemporary substituted cathinones there exists some scientific data on this chemical.

Indeed 4- CEC has a close structural relationship to diethylpropion (Amfepramone) which is sometimes prescribed in the short term management of obesity.

4-CEC has the formal and systematic IUPAC name 1-(4-chlorophenyl)-2-(ethylamino)-1-propanone, monohydrochloride. The compound has a relative molar mass of 211.7 grams and a solid at RTP. 4-CEC melts at 77.9 oC.

It belongs to the family of compounds known as substituted cathinones. The distinguishing features of this chemical family are a phenethylamine backbone along with a ketone at the beta carbon and an alkyl substituent at the alpha carbon. 4 CEC has these features. A methyl group – substituted at the alpha position. The nitrogen forms a secondary amine group with an ethyl substituent.

A chlorine atom is substituted to the benzene ring at the para position. Addition of the heavy and electronegative chlorine atom at the para position should have a number of effects on the compound. It will distort the cloud of resonance electrons having an impact on the localisation of electrostatic charge throughout the molecule.

However, not only will this modify its binding for better or worse it will also reduce the polarity of the carbonyl at the beta position. Thus making the molecule less reactive and potentially increasing half life in the body. Halogenation also affects molar mass, biological availability, lipophilicity and toxicity.


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